Meet An ABC Expert... Biotech Services ROWEL B. TOBIAS, Ph.D. Senior Scientist, Chromatography Dr. Tobias' expertise in HPLC, mass spectrometry and peptide mapping of glycoproteins provides critical information on post-translational modifications (PTM), disulfide bond analysis, glycan and glycopeptide profiling to support process and clinical drug development. His peptide mapping and intact analysis expertise provide for protein identity and purity, primary structure and MW confirmation, structural characterization and comparability of "well-characterized biologics" to comply with CMC requirements and ICH Q6B guidelines. Key Qualifications Analytical characterization of protein therapeutics/biologics by HPLC, mass spectrometry, electrophoresis and fluorescence spectroscopy to support CMC (IND) and drug development activities Physicochemical analysis of recombinant proteins and problem-solving skills in analytical assays to support CMO activities Analytical method development, qualification and transfer particularly in HPLC, ELISA and bioassay Analysis of sugars and carbohydrates by HPLC, GC-MS, enzyme and chemical assays QC release testing of recombinant proteins for pharmaceutical applications, immunoreagents (proteins and antibodies) and for FDA-cleared immunodiagnostic tests Experience in CGMP/ISO regulated manufacturing environments Knowledge of regulatory submissions, as well as GLP and CGMP compliance. Meet our other large molecule experts John C. Anders, Ph.D. Robert Marlow Brian G. Talbot Rowel B. Tobias, Ph.D. Roger D. Summers